WHY USE OF INTERVENTIONS TARGETING OUTDOOR BITING MOSQUITOES WILL BE NECESSARY TO ACHIEVE MALARIA ELIMINATION


Identification of protective pneumococcal T(H)17 antigens from the soluble fraction of a killed whole cell vaccine.

Mucosal or parenteral immunization with a killed unencapsulated pneumococcal whole cell antigen (WCA) with an adjuvant protects mice from colonization by a T(H)17 CD4+ cell-mediated mechanism.Using preparative SDS gels, we separated the soluble proteins that compose the WCA in order to identify fractions Hunter Bridle that were immunogenic and prot

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Magnetic Resonance Imaging during Proton Therapy Irradiation Allows for the Early Response Assessment of Pediatric Chordoma

Chordoma in pediatric patients is very rare.Proton therapy has become a gold standard in the treatment of these neoplasms, as high dose escalation can be achieved regarding the target while maximizing the sparing of the healthy tissues near the tumor.The aim of the work was to assess the evolution of morphological sequences during treatment using T

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Archaeal DNA Repair Mechanisms

Archaea often thrive in environmental extremes, enduring levels of heat, pressure, salinity, pH, and radiation that prove intolerable to most life.Many environmental extremes raise the propensity for DNA damaging events Coupe Mugs and thus, impact DNA stability, placing greater reliance on molecular mechanisms that recognize DNA damage and initiate

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Selenium and at-risk pregnancy: challenges and controversies

Abstract Selenium (Se), an essential trace element, is inserted as selenocysteine into an array of functional proteins and forms the core of various enzymes that play a cardinal role in antioxidant defense mechanisms, in redox regulation, and in thyroid hormone metabolism.Variations in plasma Se are due to nutritional habits, geographic and ethnic

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